Expression pattern of Thy-1.1 antigen in transgenic mice
نویسندگان
چکیده
منابع مشابه
Differential regulation of a Thy-1 gene in transgenic mice.
We have generated Thy-1.1-transgenic Thy-1.2 mice to study the developmental expression of the Thy-1 gene in detail by transcriptional and immunological methods. In brain, the expression of the injected gene was identical to that of the endogenous gene in a tissue- and development-specific manner. In lymphoid tissue, the transferred gene was also expressed correctly in the early phases of T-cel...
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Transcription of THY1 is initiated at multiple sites producing an approximately 5591 bp transcript. After splicing, the transcript is reduced to 2143 bp. Transcriptional regulation for tissue-specific expression of Thy-1, as well as for controlling expression in cell sub-populations, and in some cancers, is governed by a number of mechanisms. For tissue-specific transcriptional regulation, the ...
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ژورنال
عنوان ژورنال: Juntendo Medical Journal
سال: 1991
ISSN: 0022-6769,2188-2134
DOI: 10.14789/pjmj.37.208